An mRNA Vaccine Against SARS-CoV-2 – Preliminary Report

Jackson, LA, Anderson, EJ, Rouphael, NG, et al. (2020). N Engl J Med, DOI: 10.1056/NEJMoa2022483 AbstractBackground. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and spread globally, prompting an international effort to accelerate development of a vaccine. The candidate vaccine mRNA-1273 encodes the stabilized prefusion SARS-CoV-2 spike protein.Methods. We conducted a phase 1, dose-escalation, open-label trial including 45 healthy adults, 18 to 55 years of age, who received two vaccinations, 28 days apart, with mRNA-1273 in a dose of 25 μg, 100 μg, or 250 μg. There were 15 participants in each dose group. Results.After the Read More …

CDC Issues Alert to Doctors on Rare COVID-19 ‘Mystery Illness’ in Children

The Centers for Disease Control and Prevention issued a health alert to physicians Thursday on what has emerged as a rare but potentially deadly condition linked to COVID-19 in children. The illness, which the CDC calls “multisystem inflammatory syndrome in children,” or MIS-C, has been reported in at least 19 states and Washington, D.C. It was previously referred to as pediatric multisystem inflammatory syndrome, NBC News reports. Read more

Effects of the COVID-19 Pandemic on Routine Pediatric Vaccine Ordering and Administration — United States, 2020

On March 13, 2020, the president of the United States declared a national emergency in response to the coronavirus disease 2019 (COVID-19) pandemic (1). With reports of laboratory-confirmed cases in all 50 states by that time (2), disruptions were anticipated in the U.S. health care system’s ability to continue providing routine preventive and other nonemergency care. In addition, many states and localities issued shelter-in-place or stay-at-home orders to reduce the spread of COVID-19, limiting movement outside the home to essential activities (3). On March 24, CDC posted guidance emphasizing the importance of routine well child care and immunization, particularly for Read More …

Pediatric and adult vaccination during COVID-19

CDC has released recommendations related to pediatric and adult vaccination during COLID-19. You received the pediatric recommendations earlier (included here as well). The adult recommendations are below.  The attachment provides a statement which combines the two recommendations. Please note the websites for this information have changed since the original pediatric recommendation was released.   Delivery of Adult Clinical Preventive Services, Including Immunizations, During the COVID-19 Pandemic* https://www.cdc.gov/coronavirus/2019-ncov/hcp/preparedness-checklists.html The COVID-19 pandemic is changing rapidly and continues to affect communities across the United States differently. Clinicians must maintain access to clinical services in environments that are safe for all. Some of the Read More …

Maintaining Childhood Immunizations During COVID-19 Pandemic

The COVID-19 pandemic is changing rapidly and continues to affect communities across the United States differently. Some of the strategies used to slow the spread of disease in communities include postponing or cancelling non-urgent elective procedures and using telemedicine instead of face-to-face encounters for routine medical visits.   Ensuring the delivery of newborn and well-child care, including childhood immunization, requires different strategies. Healthcare providers in communities affected by COVID-19 are using strategies to separate well visits from sick visits. Examples include: Scheduling well visits in the morning and sick visits in the afternoon Separating patients spatially, such as by placing Read More …

Public Health Announces Additional Positive Cases of Coronavirus

DOVER (March 17, 2020) – The Delaware Division of Public Health (DPH) is announcing eight additional positive cases of coronavirus disease 2019 (COVID-19) bringing the statewide total to 16. Seven of the eight individuals are New Castle County residents, and one is the first reported case in Sussex County. Four of these individuals are males, and four are females. The ages fall within the range of 18 to 70. All but one is self-isolating at home; one in New Castle County is hospitalized. Six of the seven New Castle County residents participated in the ChristianaCare Health System drive through testing Read More …

DPH Opens Coronavirus Call Center

DOVER, DE (​March 4, 2020) – As part of the state’s response to the ongoing coronavirus disease 2019 (COVID-19) outbreak that has impacted many countries, including the U.S., the Division of Public Health (DPH) is announcing the opening of a call center at its State Health Operations Center (SHOC) in Smyrna. The call center is open to take questions from the public, schools, medical providers, state agencies and community organizations. Hours of operation will be 8:30 a.m. to 4:30 p.m. Monday through Friday. Hours may be adjusted to accommodate for peak volume. Any changes will be communicated through press release Read More …

DPH INVESTIGATING MUMPS OUTBREAK AMONG SCHOOL-AGE CHILDREN IN NEW CASTLE COUNTY

DOVER (March 4, 2020) – The Delaware Division of Public Health (DPH) is investigating an outbreak of mumps cases among school-age children in New Castle County. As of March 3, 2020, DPH had identified nine cases of mumps as part of this outbreak, including seven confirmed cases and two probable cases. The confirmed cases involve five individuals at William Penn High School, one individual at George Read Middle School, both within the Colonial School District; and one individual at St. Georges Technical High School within the New Castle County Vo-Tech School District. No additional information about those individuals will be Read More …

DPH Announces Two Negative Test Results for Coronavirus

DOVER (March 2, 2020) – The Delaware Division of Public Health (DPH) is announcing that both pending test results for coronavirus disease 2019 (COVID-19) have come back negative. These tests were the first to be run by the Delaware Public Health Laboratory, which began testing today. The results for the two individuals in Kent County, are considered presumptive negative, pending confirmatory testing by the Centers for Disease Control and Prevention (CDC). DPH will not be providing any additional information about these persons. Three Delawareans previously had been tested for COVID-19, and all three results were negative. Read more