H3N2 Component of 2017 Flu Vaccine Only 10% Effective?!
Interesting article from the New England Journal of Medicine about the effectiveness of Australia’s 2017 flu vaccine, and what doctors are seeing in the United States so far. The investigators determined that circulating influenza A (H3N2) viruses possessed an HA glycosylation site that was lost in the vaccine strain during egg adaptation, and both ferret and human antibodies elicited by that vaccine strain poorly neutralized circulating virus. The researchers also compared antibody responses elicited by vaccine antigens prepared using eggs, cell culture, and the recombinant DNA baculovirus system. They found that most people who mounted a strong antibody response to Read More …