Children’s Hospital of Philadelphia
In June 2025, the composition of the committee that makes vaccine recommendations to the CDC, known as the ACIP, was dramatically changed, as were the processes by which these recommendations were made historically. The result has been recommendations not supported by the body of scientific evidence. The January 2025 immunization schedules are the last schedules available reflecting changes made using the Evidence to Recommendations (EtR) framework, long regarded as a comprehensive and rational methodology for creating immunization recommendations. The result has been a divergence of vaccine recommendations by professional societies composed of clinicians from those made by federal officials and the CDC. To assist clinicians in staying abreast of the latest science-based recommendations, CHOP has developed a one-stop webpage that will be updated as recommendations change or as new statements become available.